Steroids are frequently prescribed by physicians for a variety of clinical disorders such as asthma, low back pain, rheumatoid arthritis, inflammatory bowel disease, M.S., and Systemic Lupus Erythematosus How To Get Rid Of Gynecomastia. Quite often, patients stay on steroids for a long duration. And end up experiencing serious side-effects, which are sometimes even worse than the original disease, such as avascular necrosis of hip or shoulder, serious infections, diabetes, high blood pressure, glaucoma, macular edema, proximal myopathy, severe osteoporosis which can lead to fragility fractures.

Steroids and Vitamin D

While there are several mechanisms how steroids can cause their side-effects, vitamin D deficiency appears to be a major pathway How to get rid of man boobs. Steroids antagonize the beneficial effects of vitamin D. For example, in bone, vitamin D enhances bone formation by stimulating osteoblasts, increasing calcium absorption from intestines and preventing secondary hyperparathyroidism. Steroids do exactly the opposite:

they have inhibitory effect on osteoblasts, decrease calcium absorption from intestines, increase calcium wasting from kidneys and cause secondary hyperparathyroidism. In this way steroids cause a rapid bone loss (osteoporosis) phentermine side effects.